Alflutop
Injections
Composition, structure and
packing
Solution for injection 1
amp. The bioactive concentrate shallow marine fish (sprat (Sprattus sprattus
sprattus), whiting Black Sea (Odontogadus merlangus euxinus), Black Sea shad
(Alosa tanaica nordmanni), Black Sea anchovy (Engraulis encrassicholus
ponticus)) 100 ml.
Excipients: Water d /, and
phenol (max. 5 mg / 1 ml).
Clinico-pharmacological group: The drug, which improves the metabolism in cartilage.
Pharmacological action
The drug, which regulates
the metabolism of cartilage tissue, chondroprotector. It is a concentrate of
bioactive shallow marine fish containing mucopolysaccharides (chondroitin
sulfate), amino acids, peptides, ions of sodium, potassium, calcium, magnesium,
iron, copper and zinc. Alflutop prevents the destruction of macromolecular
structures of normal tissues, stimulates regeneration processes in interstitial
tissue and tissue of the articular cartilage, which explains its analgesic
action.
Anti-inflammatory effect
and tissue regeneration based on the inhibition of hyaluronidase activity and
normalization of the biosynthesis of hyaluronic acid. These effects are
synergistic and cause the activation of metabolic processes in tissues,
particularly cartilage tissue, hindering the processes of degeneration.
Pharmacokinetics
Effects of extract of
marine organisms is the combined effect of its active components, so the study
of pharmacokinetic properties is not possible.
Statement
primary and secondary
osteoarthritis of different localization (including coxarthrosis, gonarthrosis,
arthrosis small joints);
spondylosis;
osteochondrosis.
Dosage regimen
The drug is prescribed for
adults.
When poliosteoartroze and
osteochondrosis Alflutop injected deep into the / m and 1 ml / day. The course
of treatment - 20 injections - 1 injection per day for 20 days.
When a primary lesion of
the large joints drug injected into the joint of 1-2 ml in each joint with an
interval between injections of 3-4 days.
The course of treatment -
5-6 injections in each joint. Perhaps a combination of V / m and intraarticular
injection. The course of treatment is advisable to repeat in 6 months.
Side effect
Rare: dermatitis, itching,
redness, burning sensation at the injection site, short-myalgia. Very rare:
anaphylactic reaction. In some cases: transient amplification of pain (when
intraarticular injection).
Contraindications
Pregnancy
Lactation (breastfeeding);
childhood;
Hypersensitivity to the
drug's components.
We do not recommend use of
the drug in children because of lack of data from clinical studies in this
patient.
Cautions
In the case of individual
intolerance of seafood (sea fish) increases the risk of allergic reactions.
Overdose
Symptoms: in predisposed
patients may be allergic reactions, sometimes severe course.
Treatment: removal of
preparation, conduct of symptomatic therapy.
Terms and Conditions of
storage
The drug should be stored
out of reach of children, protected from light at temperature of 15 ° to 25 °
C.
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